Acta Chir Orthop Traumatol Cech. 1998; 65(4):207-210

[The response of methylprednisolon therapy to interleukin-6 release in spinal injuries.].

P Visna, P Wendsche, P Svoboda, I Kantorová
Spinální jednotka Urazové nemocnice, Brno.

The prospective study continues the investigations published in "Dynamics of Cytokines in the Blood and Liquor at the Spinal Injured Patients". In previous publication we documented a statistical significant dependence of IL-6 concentration in the blood and liquor to various degrees of neurological lesion classified by Frankel scale. We followed the influence of Methylprednisolon (Solumedrol, UpJohn) therapy to the IL-6 level in blood and liquor, as the supposed selective mediator for spinal trauma. In investigated group we documented the positive influence of Solumedrol therapy to final neurological status and significant decrease of IL-6 liquor concentration in this patients. Key words: lnterleukin-6, Methylprednisolon, Frankel scale, spinal cord injury.

Zveřejněno: 1. leden 1998  Zobrazit citaci

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Visna P, Wendsche P, Svoboda P, Kantorová I. [The response of methylprednisolon therapy to interleukin-6 release in spinal injuries.]. Acta Chir Orthop Traumatol Cech. 1998;65(4):207-210. PubMed PMID: 20492795.
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