Acta chirurgiae orthopaedicae
et traumatologiae Čechoslovaca

Acta Chir Orthop Traumatol Cech. 2015; 82(4):293-295 | DOI: 10.55095/achot2015/045

Snížení totální antioxidační kapacity po zlomenině femuruPůvodní práce

D. KESKIN^1,*, A. KIZILTUNC²

¹ Department of Orthopaedics and Traumatology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey

² Department of Biochemistry, Ataturk University, Faculty of Medicine, Erzurum, Turkey

PURPOSE OF THE STUDY:
The aim of this study was to determine the changes in total antioxidant capacity (TAC) during the fracture healing process.

MATERIAL AND METHODS:
Twenty patients with isolated closed femoral fracture, between the ages 18 and 60 years, were included in the study. The control group was formed with healthy volunteers. Venous blood was drawn from the healthy volunteers once, and from the patients five times during 14 days after fracture. TAC was measured in the sera of these samples.

RESULTS:
In the patient group, the serum TAC was the highest in the first 6 hours, whereas there was a decreasing trend on the 3^rd, 7^th and 14^th days, and an increasing trend on the 5^th day. The mean serum TAC in all measurements of the patient group were lower than those in the control group.

CONCLUSION:
The present study suggests that TAC may be decreased in considerable amounts during the first 2 weeks of fracture healing.

Klíčová slova: human bone, fracture, blood, total antioxidant capacity

Zveřejněno: 1. srpen 2015  Zobrazit citaci