Acta Chir Orthop Traumatol Cech. 2016; 83(1):21-26 | DOI: 10.55095/achot2016/003

Musculoskeletal Pain and Vitamin D Deficiency in Children: A Pilot Follow-up Study of Vitamin D Therapy in Musculoskeletal/Orthopedic ConditionsOriginal papers

Z. BLAGOJEVIC1, V. NIKOLIC1, D. KISIC-TEPAVCEVIC2, Z. TERZIC SUPIC3, R. KOVACEVIC1, Z. ZIVKOVIC4, D. STEVANOVIC5,*
1 Institute for Orthopedic Surgery "Banjica", Belgrade, Serbia
2 Institute of Epidemiology, Belgrade University, School of Medicine, Belgrade, Serbia
3 Institute of Social Medicine, Belgrade University, School of Medicine, Belgrade, Serbia
4 Children's Hospital for Lung Diseases and Tuberculosis, Medical Center Dr "Dragisa Misović", Belgrade, Serbia
5 Clinic for Neurology and Psychiatry for Children and Youth, Belgrade, Serbia

PURPOSE OF THE STUDY:
The prevalence of vitamin D deficiency in pediatric populations is high. In the present study we analyzed associations between vitamin D therapy and pain, mobility, fatigue, and daily functioning in children with musculoskeletal/orthopedic conditions suffering from chronic and recurrent pain, but also diagnosed with vitamin D deficiency.

MATERIAL AND METHODS:
Children with different musculoskeletal/orthopedic conditions and vitamin D deficiency were prescribed to receive vitamin D over 6 months. Thirty-five children (18 males; age 10.48 ± 3.87 years) completed a 6-month follow-up. Self- and parent/proxy rating scales were used to evaluate pain, movement, fatigue, and daily functioning.

RESULTS:
At a six-month follow-up assessment involving child- and parent-reported scores, worst pain intensity significantly decreased (p ≤ 0.03) after vitamin D therapy, as well as functioning problems related to pain (p ≤ 0.01). The children reported better movement and balance with less fatigue. The parents reported better functioning in everyday activities of their children.

CONCLUSION:
This pilot study showed that vitamin D therapy possibly reduces pain intensity and improves mobility and daily functioning in children with musculoskeletal/orthopedic disorders, chronic recurrent pain, and vitamin D deficiency. Further follow-up and randomized studies are required in order to assess the validity of clinical recommendations.

Keywords: vitamin D, pain, musculoskeletal disorders, children, adolescents

Published: February 1, 2016  Show citation

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BLAGOJEVIC Z, NIKOLIC V, KISIC-TEPAVCEVIC D, TERZIC SUPIC Z, KOVACEVIC R, ZIVKOVIC Z, STEVANOVIC D. Musculoskeletal Pain and Vitamin D Deficiency in Children: A Pilot Follow-up Study of Vitamin D Therapy in Musculoskeletal/Orthopedic Conditions. Acta Chir Orthop Traumatol Cech. 2016;83(1):21-26. doi: 10.55095/achot2016/003. PubMed PMID: 26936061.
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