Acta Chir Orthop Traumatol Cech. 2022; 89(6):435-440 | DOI: 10.55095/achot2022/069

Deep Venous Thrombosis after Conservative Treatment of Clavicular Fracture in COVID-19 Negative Children: Two Case ReportsCase report

M. SALÁŠEK1,2,*, T. PAVELKA1, D. WEISOVÁ1,2
1 Department of Orthopaedics and Traumatology of Motoric Apparatus, Faculty Hospital in Plzeň, Plzeň, Czech Republic
2 NTIS (New Technologies for the Information Society - European Centre of Excellence), University of West Bohemia, Plzeň, Czech Republic

A 13-year-old girl suffered fracture of her left clavicle. A figure-of-8 bandage was placed during initial treatment. Six days after trauma her distal arm, elbow and proximal forearm were swollen, pain and tenderness of distal part of brachial vein was recognized during clinical examination. Duplex ultrasonography revealed partial thrombosis of the brachial vein. Bandage was immediately removed and administration of LMWH (enoxaparin) was started. Complete recanalization was achieved after a few days. The fracture was healed without further complication, patient was without sonographic and clinical signs of post-thrombotic syndrome. The second case report describes a 14-year-old boy. Initially, the fixation was a figure-of-8 bandage. 5 days after the injury he had swollen arm and elbow on the injured side, according to duplex ultrasonography deep venous thrombosis of the axillary and the brachial vein was recognized. There was only partial recanalization at the first sonographic follow up, the patient was converted to Warfarin for 3 months after injury after initial LMWH therapy. At the last follow-up, fracture of the left clavicle was healed and there were no DUSG or clinical signs of post-thrombotic syndrome.

Keywords: clavicle, deep venous thrombosis of the upper extremity, anticoagulant therapy

Published: December 15, 2022  Show citation

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SALÁŠEK M, PAVELKA T, WEISOVÁ D. Deep Venous Thrombosis after Conservative Treatment of Clavicular Fracture in COVID-19 Negative Children: Two Case Reports. Acta Chir Orthop Traumatol Cech. 2022;89(6):435-440. doi: 10.55095/achot2022/069. PubMed PMID: 36594691.
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References

  1. Avila L, Amiri N, De R, Vincelli J, Pullenayegum EM, Williams S, Brandao LR. Characteristics of upper and lower extremity deep vein thrombosis and predictors of post-thrombotic syndrome in children. Blood Adv. 2021;5:3737-3747. doi: 10.1182/bloodadvances.2021004727. Go to original source... Go to PubMed...
  2. Buchanan DAS, Owen D, Angliss R, McClure DN. Acute subclavian artery occlusion with associated clavicle fracture managed with bypass graft alone. BMJ Case Rep. 2018;2018:bcr2018224719. doi: 10.1136/bcr-2018-224719. Go to original source... Go to PubMed...
  3. Coughlin LM, Koenig KN, Clark PM. Claviculectomy with thrombectomy for management of paget-schroetter syndrome in a patient with chronic clavicular malunion. Ann Vasc Surg. 2013;27:498.e1-4. doi:10.1016/j.avsg.2012.09.008. Go to original source... Go to PubMed...
  4. Davidovic LB, Kostic DM, Jakovljevic NS, Kuzmanovic IL, Simic TM. Vascular thoracic outlet syndrome. World J Surg. 2003;27:545-550. Go to original source... Go to PubMed...
  5. Davidović L, Lotina S, Kostić D, Pavlović S, Jakovljević N, Djorić P. [The upper thoracic outlet vascular syndrome]. Acta Chir Iugosl. 2001;48:31-36. Go to PubMed...
  6. Kumar R, Harsh K, Saini S, O'Brien SH, Stanek J, Warren P, Giver J, Go MR, Kerlin BA. Treatment-related outcomes in Paget-Schroetter syndrome - a cross-sectional investigation. J Pediatr. 2019;207:226-232.e1. doi: 10.1016/j.jpeds.2018.11.018. Go to original source... Go to PubMed...
  7. Lyons MM, Holzmeister AM, Cappello T. Nonoperative management of subclavian artery thrombosis in pediatric clavicle fractures: a case report. JBJS Case Connect. 2021;11. doi: 10.2106/JBJS.CC.20.00815. Go to original source... Go to PubMed...
  8. Mollano AV, Hagy ML, Jones KB, Buckwalter JA. Unusual osteochondroma of the medial part of the clavicle causing subclavian vein thrombosis and brachial plexopathy. A case report. J Bone Joint Surg Am. 2004;86:2747-2750. Go to original source... Go to PubMed...
  9. Mustafa J, Asher I, Sthoeger Z. Upper extremity deep vein thrombosis: symptoms, diagnosis, and treatment. Isr Med Assoc J. 2018;20:53-57. Go to PubMed...
  10. Nayar SK, Kuwabara AM, Flores JM, Osgood GM, LaPorte DM, Shafiq B. Venous thromboembolism in upper extremity fractures. J Hand Surg Asian Pac Vol. 2018;23:320-329. doi: 10.1142/S2424835518500303. Go to original source... Go to PubMed...
  11. O'Brien S. A silent response to silent thrombosis. Blood. 2019;133:776-777. doi: 10.1182/blood-2018-11-884288. Go to original source... Go to PubMed...
  12. Peivandi MT, Nazemian Z. Clavicular fracture and upper-extremity deep venous thrombosis. Orthopedics. 2011;34:227. doi: 10.3928/01477447-20110124-28. Go to original source... Go to PubMed...
  13. Ranke H, Märdian S, Haas NP, Baecker H. [Thrombosis of the subclavian vein after conservative treatment of a clavicular fracture: a rare complication]. Unfallchirurg. 2016;119:255-258. doi: 10.1007/s00113-015-0091-y. Go to original source... Go to PubMed...
  14. Samineni AV, Sanborn R, Shea J, Cook D, May CJ, Heyworth BE, Shore BJ. Pediatric venous thromboembolism: different rates of incidence, anatomic locations, and risk factors between orthopaedic and nonorthopaedic related patients. J Pediatr Orthop. 2021;41:379-384. doi: 0.1097/BPO.0000000000001810. Go to original source... Go to PubMed...
  15. Weh L, von Torklus D. [Dislocated clavicle fracture with a costoclavicular compression syndrome]. Z Orthop Ihre Grenzgeb. 1980;118:140-142. Go to original source... Go to PubMed...
  16. Whitworth H, Sartain SE, Kumar R, Armstrong K, Ballester L, Betensky M, Cohen CT, Diaz R, Diorio C, Goldenberg NA, Jaffray J, Keegan J, Malone K, Randolph AG, Rifkin-Zenenberg S, Leung WS, Sochet A, Srivaths L, Zia A, Raffini L. Rate of thrombosis in children and adolescents hospitalized with COVID-19 or MIS-C. Blood. 2021;138:190-198. doi: 10.1182/blood.2020010218. Go to original source... Go to PubMed...