Acta Chir Orthop Traumatol Cech. 2025; 92(4):203-209 | DOI: 10.55095/achot2024/069

Septic Arthritis of the Wrist Joint: Cohort of Patients Treated between 2003 and 2023, Guidelines for the Diagnosis and TreatmentOriginal papers

LUCIE PAPEŽOVÁ, ZDENĚK VODIČKA, DAVID MUSIL, JAN KLOUDA
Ortopedické oddělení, Nemocnice České Budějovice, a.s.

Purpose of the study: The study aimed to evaluate the timeliness and effectiveness of treatment of all patients who underwent surgery for septic arthritis of the wrist at our department between 2003 and 2023.

Material and methods: The retrospective study included 38 patients (26 men and 12 women). The mean age of the patients was 68 years. All patients underwent surgery for culture-positive arthritis of the native wrist. Patients with periprosthetic and extraarticular infections were excluded from the study. Once the diagnosis was established based on the clinical examination and laboratory analysis of blood and synovial fluid, antibiotic treatment was administered and revision surgery was performed. Arthroscopic procedure was used in the unaffected wrist, whereas open surgery was opted for in case of any degenerative changes of the wrist joint and extra-articular spread of infection. A total of 50 surgeries were performed, of which 6 arthroscopies, 32 open arthrotomies, 2 open surgeries with proximal row carpectomy, 6 open surgeries with simultaneous resection arthrodesis, 2 revision surgeries with arthrodesis via internal fixation for prolonged healing, 2 revision surgeries for another postoperative complication.

Results: In our study cohort of patients with septic arthritis, the arthritis of the wrist represented 7%. The most common pathogen was Staphylococcus aureus (60.5%). In 35 patients (92%) at least one risk factor for septic arthritis was present. In all patients, signs of local inflammation were present. 17 patients showed signs of system-wide inflammation and in 32 patients laboratory markers of inflammation were reported. In 6 cases both sides were affected. In our cohort the lethality reached 8%. These were patients with severe immunodeficiency and multiple loci of infection. Full recovery was achieved in 35 patients (92%), i.e. in all surviving patients, in whom the wrist joint was stable upon treatment completion and the self-care was not limited.

Discussion: The prevailing part of the patients (92.10%) with septic arthritis of the wrist showed risk factors for the development of septic arthritis, i. e. poor overall health condition of the patient, immunosuppression, organ failure, diabetes, age over 65 years, rheumatoid arthritis, surgery or trauma, drug or alcohol abuse. In case of bacteremia or sepsis, the risk factors include also chronic degenerative or inflammatory changes in the wrist region, with synovitis constituting a predisposition for hematogenous spread of septic arthritis of the wrist. Our cohort clearly confirms that the system-wide signs and laboratory markers of inflammation are nonspecific markers which cannot conclusively confirm the diagnosis of septic arthritis of the wrist, but the development of their values over time demonstrates the effect of treatment used. The presence of degenerative changes of the wrist joint influences the choice of surgical procedure.

Conclusions: Septic arthritis of the wrist ranks among the less common types of arthritis. Early diagnosis should promptly be followed by adequate surgical treatment. Correct early management increases the likelihood of full recovery, even in high-risk patients.

Keywords: infection, arthritis, wrist, diagnosis, treatment.

Received: October 22, 2024; Revised: October 22, 2024; Accepted: November 7, 2024; Published: August 1, 2025  Show citation

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PAPEŽOVÁ L, VODIČKA Z, MUSIL D, KLOUDA J. Septic Arthritis of the Wrist Joint: Cohort of Patients Treated between 2003 and 2023, Guidelines for the Diagnosis and Treatment. Acta Chir Orthop Traumatol Cech. 2025;92(4):203-209. doi: 10.55095/achot2024/069. PubMed PMID: 40878451.
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References

  1. Berger RA, Bishop AT, Bettinger PC. New dorsal capsulotomy for the surgical exposure of the wrist. Ann Plast Surg. 1995;35:54-59. Go to original source... Go to PubMed...
  2. Claiborne JR, Branch LG, Reynolds M, Defranzo AJ. An algorithmic approach to the suspected septic wrist. Ann Plast Surg. 2017;78:659-662. Go to original source... Go to PubMed...
  3. Hariri A, Lebailly F, Zemirline A, Hendriks S, Facca S, Liverneaux P. Contribution of arthroscopy in case of septic appearance arthritis of the wrist: a nine cases series. Chir Main. 2013;32:240-244. Go to original source... Go to PubMed...
  4. Horowitz DL, Katzap E, Horowitz S, Barilla-LaBarca ML. Approach to septic arthritis. Am Fam Physician. 2011;84:653-660.
  5. Chenoweth B. Septic joints: finger and wrist. In: Chung KC. Hand infections. Elsevier, Philadelphia, 2020, pp 332-338. Go to original source...
  6. Jennings JD, Ilyas AM. Septic arthritis of the wrist. J Am Acad Orthop Surg. 2018;26:109-115. Go to original source... Go to PubMed...
  7. Kang G, Leow MQH, Tay SC. Wrist inflammation: a retrospective comparison between septic and non-septic arthritis. J Hand Surg Eur. 2018;43:431-437. Go to original source... Go to PubMed...
  8. Klein DS, Yingling JM, Patel P, Capo JT. Vacuum-assisted therapy fo combined volar-dorsal soft tissue defects of the hand: a case report. Adv Skin Wound Care. 2022;35:57-61. Go to original source... Go to PubMed...
  9. Kowalski TJ, Thompson LA. Antimicrobial management of septic arthritis of the hand and wrist. Infection. 2014;42:379-384. Go to original source... Go to PubMed...
  10. Manadan AM, Block JA. Daily needle aspiration versus surgical lavage for the treatment of bacterial septic arthritis in adults. Am J Ther. 2004;11:412-415. Go to original source... Go to PubMed...
  11. Mehta P, Schnall SB, Zalavras CG. Septic arthritis of the shoulder, elbow, and wrist. Clin Orthop Relat Res. 2006;45:42-45. Go to original source... Go to PubMed...
  12. Meier R, Lanz U. Septic arthritis of the wrist. Handchir Mikrochir Plast Chir 2007;39:112-117. Go to original source... Go to PubMed...
  13. Michelotti BF, Chung KC. Diagnostic wrist arthroscopy. Hand Clin. 2017;33:571-583. Go to original source... Go to PubMed...
  14. Musil D, Chrdle A, Horníková M, Balejová M, Klouda J, Pertlíček J, Trnka T. Native joint septic arthritis in adults: incidence in our group of patients and antibiotic therapy guidelines. Acta Chir Orthop Traumatol Cech. 2021;88:354-361. Go to original source...
  15. Sharma V, Sharma A. Infectious mimics of rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2022;36:101736. Go to original source... Go to PubMed...
  16. Skeete K, Hess EP. Epidemiology of suspected wrist joint infection versus inflammation. J Hand Surg Am. 2011;36:469-474. Go to original source... Go to PubMed...
  17. Smith JW, Chalupa P, Shabaz Hasan M. Infectious arthritis: clinical features, laboratory findings and treatment. Clin Microbiol Infect. 2006;4:309-314. Go to original source... Go to PubMed...
  18. Triki MA, Naouar N, Benzarti S, Kaziz H, Mouelhi T, Ayeche MLB. Septic arthritis of the wrist: about six cases. Pan Afr Med J. 2019;19:33:237. Go to original source... Go to PubMed...
  19. Vodička Z. Septická artritida zápěstí. In: Musil D, Gallo J, Chrdle A. Infekce v ortopedii. Jessenius, Praha, 2022, pp 246-247.
  20. Weston VC, Jones AC, Bradbury N, Fawthrop F, Doherty M. Clinical features and outcome of septic arthritis in a single UK Health District 1982-1991. Ann Rheum Dis. 1999;58:214-219. Go to original source... Go to PubMed...
  21. Wolfe SW, Pederson WC, Hotchkiss RN, Kozin, SH. Acute infections of the hand. In: Stevanovic MV, Sharpe FE. Green's operative hand surgery. Elsevier, Philadelphia, 2917, pp 45-67.
  22. Yap RT, Tay SC. Wrist septic arthritis: an 11 year review. Hand Surg. 2015;2:391-395. Go to original source... Go to PubMed...