Acta Chir Orthop Traumatol Cech. 2007; 74(3):162-170 | DOI: 10.55095/achot2007/026

Využití muskulárního laloku při léčení infikovaných zlomenin a chronické osteomyelitidy v oblasti bérce a hleznaPůvodní práce

A. NEJEDLÝ1,*, V. DŽUPA2, J. ZÁHORKA2, M. TVRDEK1
1 Klinika plastické chirurgie 3. LF UK a FNKV, Praha
2 Ortopedicko-traumatologická klinika 3. LF UK a FNKV, Praha

PURPOSE OF THE STUDY:
The aim of the study was to evaluate the results of treatment in patients with infected fractures or chronic osteomyelitis in the tibial and ankle regions by radical debridement of skeletal and soft tissues and coverage of the defect, using free flap transfer or muscle flap transposition.

MATERIAL:
Between January 1, 2002 and December 31, 2004, 26 patients were treated by this method; 13 had infected tibial or ankle fractures and 13 showed osteomyelitis of the tibia. All patients, in the case of failure, would have been indicated for below-knee amputation. The group comprised six women and 20 men at an average age of 46 years (range, 10 to 67 years).

METHODS:
In this retrospective study, the following data were recorded: type of injury (multiple trauma, combined trauma, single trauma), fracture type according to the AO classification, grade of injury in open fractures by the Gustillo and Anderson classification, number of previous operations in patients with infected fractures, microbiological findings in all patients before defect coverage with a flap, interval between the injury and flap coverage, number of post-operative complications, number of subsequent operations, period of relief for the treated limb, actual weight-bearing of the limb, patient's satisfaction with the therapy.

RESULTS:
Since one patient died of heart attack during follow-up, 25 patients (5 women and 20 men) were included in the final evaluation. The average follow-up was 27 months (range, 15 to 49 months). The healing of infection and union of bone were recorded in 21 patients (84 %). Healing with pseudoarthrosis development occurred in three patients (12 %). One patient (4 %) had to undergo leg amputation due to persistent secretion. The duration of treatment before coverage of the defect was on average 10 weeks (range, 4 weeks to 6 months) in the patients with infected fractures, and 9 years (range, 2 to 20 years) in the patients with osteomyelitis.
Post-operative complications were recorded in seven patients (27 %). Impaired vascularization of the flap in the early post-operative period was found in two patients (8 %). In two patients (8 %) residual infected tissue under the flap resulted in purulent secretion. In three patients (12 %), at the time of evaluation, the lower extremity could not bear weight due to non-union of fractured bone.

DISCUSSION:
The use of free or transposition muscle is regarded as the optimal method for the treatment of extensive defects of soft tissues in limb traumatology. The advantages include: good quality coverage of the defect; ability of vascularized flap tissue to transport antibiotic to the defect area; long-term improved perfusion in the fracture region is important for fracture healing.

CONCLUSIONS:
The treatment of infected tibial and malleolar fractures by debridement and subsequent coverage of soft tissue defects, using muscle flap transfer, permits elimination of infection in most of the patients, but often requires subsequent surgery in order to provide biological stimulation for healing of defective fractures. Treatment of osteomyelitis of the tibia by this method is demanding, but has a good prospect of healing in a period shorter than is necessary for treatment without muscle flap transfer.

Klíčová slova: infected tibial fractures, osteomyelitis of the tibia, inter-disciplinary care, debridement, defect coverage, muscle flap, free muscle transfer, muscle transposition

Přijato: 25. únor 2007; Zveřejněno: 1. červen 2007  Zobrazit citaci

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
NEJEDLÝ A, DŽUPA V, ZÁHORKA J, TVRDEK M. Využití muskulárního laloku při léčení infikovaných zlomenin a chronické osteomyelitidy v oblasti bérce a hlezna. Acta Chir Orthop Traumatol Cech. 2007;74(3):162-170. doi: 10.55095/achot2007/026. PubMed PMID: 17623603.
Stáhnout citaci

Reference

  1. GASTMEIER, P., SOHR, D., BRANDT, C., ECKMANNS, T., BEHNKE, M., RÜDEN, H.: Reduction of orthopaedic wound infections in 21 hospitals. Arch. Orthop. Trauma Surg., 125: 526-530, 2005. Přejít k původnímu zdroji... Přejít na PubMed...
  2. GONZALEZ, M.H., TARANDY, D.I., TROY, D., PHILLIPS, D., WEINZWEIG, N.: Free tissue coverage of chronic traumatic wounds of the lower leg. Plast. Reconstr. Surg., 109: 592-600, 2002. Přejít k původnímu zdroji... Přejít na PubMed...
  3. GUSTILLO, R.B., ANDERSON, J.T.: Prevention of infection in the treatment of bone thousand and twenty-five opet fractures of long bones: Retrospective and prospective analysis. J. Bone Jt Surg., 58-A: 453-458, 1976. Přejít k původnímu zdroji...
  4. HARLEY, B.J., BEAUPRE, L.A., JONES, C.A., DULAI, S.K., WEBER, D.W.: The effect of time to definitive treatment on the rate of nonunion and infection in open fractures. J. Orthop. Trauma, 16: 484-490, 2002. Přejít k původnímu zdroji... Přejít na PubMed...
  5. CHEN, C.-E., KO, J.-Y., PAN, C.-C.: Results of vancomycin-impregnated cancellous bone grafting for infected tibial nonunion. Arch. Orthop. Trauma Surg., 125: 369-375, 2005. Přejít k původnímu zdroji... Přejít na PubMed...
  6. JAEGER, K., GIEBEL, G.D.: Treatment of osteomyelitis using free myocutaneous flap in the lower leg. Handchir. Mikrochir. Plast. Chir., 19: 104-108, 1987.
  7. KHOURI, R.K., SHAW, W.W.: Reconstruction of the lower extremity with microvascular free flaps: A 10-year experience with 304 consecutive cases. J. Trauma, 29: 1086-1094, 1987. Přejít k původnímu zdroji... Přejít na PubMed...
  8. KUOKKANEN, H.O., TUKIAINEN, E.J., ASKO-SELJAVAARA, S.: Radical excision and reconstruction of chronic tibial osteomyelitis with microvascular muscle flaps. Orthopedics, 25: 137-140, 2002. Přejít k původnímu zdroji... Přejít na PubMed...
  9. KUTSCHA-LISSBERG, F., HEBLER, U., KALICKE, T., ARENS, S.: Principles of surgical therapy concepts for postoperative and chronic osteomyelitis. Orthopäde, 33: 439-454, 2004. Přejít k původnímu zdroji... Přejít na PubMed...
  10. MÜLLER, M.E., NAZARIAN, S., KOCH, P., SCHATZKER, J.: The comprehensione classification of fractures of long bones. Berlin, Heidelberg, New York, Springer-Verlag 1990. Přejít k původnímu zdroji...
  11. NAIQUE, S.B., PERSE, M., NANCHAHAL, J.: Management of severe open tibial fractures. The need for combinated orthopaedic and plastic surgical treatment in specialist centers. J. Bone Jt Surg., 88-B: 351-357, 2006. Přejít k původnímu zdroji... Přejít na PubMed...
  12. NEJEDLÝ, A., TVRDEK, M., STEHLÍK, J.: Závěrečná zpráva grantu IGA MZ ČR 1651-3 "Význam užití časných tkáňových přenosů při komplexní léčbě defektních poranění dolní končetiny". Praha, 3. LF UK 1995.
  13. NEUBAUER, T., BAYER, G.S., WAGNER, M.: Open fractures and incection. Acta Chir. orthop. Traum. čech., 73: 301-312, 2006. Přejít k původnímu zdroji...
  14. OCHSNER, P.E., MÜLLER, U.: Acute Infection. In: RÜEDI, T.P., MURPHY, W.M. (Eds): AO Principles of Fracture Management. Stuttgart, New York, Thieme 2000, 729-747.
  15. PROS, Z., TVRDEK, M., KLETENSKÝ, J., NEJEDLÝ, A., SVOBODA, S.: Chronic traumatic wounds of the leg. Acta Chir. Plast., 38: 83-86, 1996.
  16. SALVANA, J., RODNER, C., BROWNER, B.D., LIVINGSTON, K., SCHREIBER, J., PESANTI, E.: Chronic osteomyelitis: Results obtained by an integrated team approach to management. Conn. Med., 69: 195-202, 2005.
  17. TVRDEK, M., NEJEDLÝ, A., KLETENSKÝ, J., KUFA R.: Treatment of chronic osteomyelitis of the lower extremity using free flap transfer. Acta Chir. Plast., 41: 46-49, 1999.
  18. WILLENEGGER, H., ROTH, B.: Behandlungstaktik und Spätergebnisse bei Frühinfekt nach Osteosynthese. Unfallchirurgie, 12: 241-246, 1986. Přejít k původnímu zdroji... Přejít na PubMed...
  19. ZEMAN, J., MATĚJKA, J.: Použití hybridního zevního fixátoru u zlomenin bérce. Acta Chir. orthop. Traum. čech., 72: 337-343, 2005.