Acta Chir Orthop Traumatol Cech. 2023; 90(1):63-66 | DOI: 10.55095/achot2023/010
High-Grade chondrosarkom proximálního článku: neobvyklý případ vzácné entityKazuistika
- 1 Hand and Microsurgery Unit of the Jewish Hospital of Rome, Rome, Italy
- 2 Pathology Unit of the Jewish Hospital of Rome, Rome, Italy
- 3 Villa Stuart Eurosanità, Rome, Italy
- 4 Department of Anatomical, Histological, Forensic Medicine and Orthopaedic Science, Sapienza University of Rome, Rome, Italy
- 5 IRCCS Regina Elena National Cancer Institute, Rome, Italy
Chondrosarcoma of the hand is a rare disease, but is one of the more common malignancies of the hand. Biopsies and imaging are a fundamental step in determining correct diagnosis, grading and selection for best treatment.
We describe the case of a 77-year-old male complaining of a painless swelling in the proximal phalanx of the third ray of left hand. A biopsy was performed and the histology revealed a G2 chondrosarcoma. The patient underwent III ray amputation with metacarpal bone disarticulation and sacrifice of the radial digit nerve of the fourth ray. Definitive histology revealed grade 3 CS. Eighteen months after surgery, the patient is apparently disease-free with a good functional and aesthetic outcome although with persistent paresthesia of the fourth ray.
Although there is no agreement in the literature for the treatment of low-grade chondrosarcomas, wide resection or amputation can be considered the mainstay treatment for high-grade tumors.
Klíčová slova: chondrosarcoma, proximal phalanx, ray amputation, surgical treatment, tumor hand
Zveřejněno: 15. únor 2023 Zobrazit citaci
ACS | AIP | APA | ASA | Harvard | Chicago | Chicago Notes | IEEE | ISO690 | MLA | NLM | Turabian | Vancouver |
Reference
- Annovazzi A, Anelli V, Zoccali C, Rumi N, Persichetti A, Novello M, Sciuto R, Bertoni F, Ferraresi V, Biagini R. 18F-FDG PET/CT in the evaluation of cartilaginous bone neoplasms: the added value of tumor grading. Ann Nucl Med. 2019;33:813-821.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Bovée JV, van der Heul RO, Taminiau AH, Hogendoorn PC. Chondrosarcoma of the phalanx: a locally aggressive lesion with minimal metastatic potential: A report of 35 cases and a review of the literature. Cancer. 1999;86:1724-1732.
Přejít k původnímu zdroji...
- Evans HL, Ayala AG, Romsdahl MM. Prognostic factors in chondrosarcoma of bone: a clinicopathologic analysis with emphasis on histologic grading. Cancer. 1977;40:818-831.
Přejít k původnímu zdroji...
- Hickey M, Farrokhyar F, Deheshi B, Turcotte R, Ghert M. A systematic review and meta-analysis of intralesional versus wide resection for intramedullary grade I chondrosarcoma of the extremities. Ann Surg Oncol. 2011;18:1705-1709.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Lesenský J, Matejovsky ZJ, Vcelak J, Ostadal M, Hosova M, Bavelou C, Sioutis S, Bekos A, Mavrogenis AF. Chondrosarcomas of the small bones: analysis of 44 patients. Eur J Orthop Surg Traumatol. Epub 2021 Apr 3. 2021;31:1597-1602. doi: 10.1007/s00590-021-02964-8.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Mankin HJ. Chondrosarcomas of digits: are they really malignant? Cancer. 1999;86:1635-1637.
Přejít k původnímu zdroji...
- Mittermayer, F., Dominkus, M., Krepler, Schwameis E, Sluga M, Toma C, Lang S, Grampp S, Kotz R. Chondrosarcoma of the Hand: Is a Wide Surgical Resection Necessary? Clin Orthop Relat Res. 2004;424:211-215.
Přejít k původnímu zdroji...
- Patil S, de Silva MV, Crossan J, Reid R. Chondrosarcoma of small bones of the hand. J Hand Surg Br. 2003;28:602-628.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Puhaindran ME, Healey JH, Athanasian EA. Single ray amputation for tumors of the hand. Clin Orthop Relat Res. 2010;468:1390-1395.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Stomeo, D. Tulli A, Ziranu A, Mariotti F, Maccauro G. Chondrosarcoma of the hand: a literature review. J Cancer Ther. 2014;5:403-409.
Přejít k původnímu zdroji...
- Zoccali C, Baldi J, Attala D, Rossi B, Anelli V, Annovazzi A, Ferraresi V. Intralesional vs. extralesional procedures for low-grade central chondrosarcoma: a systematic review of the literature. Arch Orthop Trauma Surg. 2018;138:929-937.
Přejít k původnímu zdroji...
Přejít na PubMed...